Epilepsy is not only a common, often devastating disease but also a comorbidity of many neurological disorders, in which control of seizures may significantly improve quality of life and even prognosis. Recent years have witnessed major advancements in the identification of the mechanisms of disease that hold the promise to lead to new treatments. Organised by the FENS Committee for Higher Education and Training (CHET), this FENS Friday webinar provided an overview of these findings and of their potential implications not only for epilepsy but also for other neurological diseases.